APRI (aspartate aminotransferase [AST]-to-platelet ratio index) is recommended as the preferred non-invasive test (NIT) to assess for the presence of cirrhosis (APRI score >2 in adults) in resource-limited settings. Transient elastography (e.g. FibroScan) or FibroTest may be the preferred NITs in settings where they are available and cost is not a major constraint.

APRI Score Caculator






APRI Score = (AST/AST ULN) x 100) / platelet count (109/L)

Your ARPI Score :


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Interpretation:

APRI score >2 in adults


APRI score > 2 is 89% specific in detecting cirrhosis (F4). With a sensitivity of 35%, an APRI value > 2 can miss two thirds with cirrhosis. APRI score > 1 is more sensitive (65%) but is less specific (75%) in detecting cirrhosis. APRI score > 1.5 is 92% specific but can miss almost two thirds with significant hepatic fibrosis (F2-F4). (Guidelines for the prevention, care and treatment of persons with chronic hepatitis B infection. 2015, WHO)