Interpretation: FIB-4 score > 3.6 has a 90.8% positive predictive value with 98% specificity and 30% sensitivity in detecting cirrhosis, whereas FIB-4 score < 1.6 has a negative predictive value of 93% in detecting cirrhosis. FIB 4 > 2.6 has a 94.6% positive predictive value and 97.8% specificity in detecting severe liver fibrosis (> F3).
(Kim BK et al. Liver International 2009)